The effect of those channels on neuron firing fee in nigral dopamine neurons is these types of that administration of your KATP-channel antagonist glibenclamide at a 100 nM focus was able to improve neuron firing charge by 34% (Garcia de Arriba et al 1999; Avshalumov et al 2005). KATP-channel action also seems being enhanced by extracellular adenos

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